Skip to main content
. 2023 Mar 5;14(4):657–664. doi: 10.7150/jca.81616

Table 4.

Risk factors for PTB in patients with lung cancer involving different cell types.

Variable Non-small cell Small cell
AHR (95% CI) AHR1 (95% CI) AHR (95% CI) AHR1 (95% CI)
Sex
Male vs. Female 2.0*(1.7-2.3) 1.7*(1.5-2.0) 1.7(0.8-3.6) 1.7(0.8-3.8)
Age(years)
<50 Ref Ref Ref Ref
50-59 1.2(0.9-1.5) 1.2(0.9-1.5) 1.0(0.4-2.5) 1.1(0.4-2.7)
60-69 1.6*(1.2-2.0) 1.5*(1.2-1.9) 0.9(0.4-2.2) 0.9(0.4-2.3)
≥70 2.3*(1.8-2.9) 1.9*(1.5-2.4) 1.5(0.7-3.6) 1.4(0.6-3.3)
Clinical stage
I Ref Ref Ref Ref
II 1.4*(1.1-1.8) 1.2(0.9-1.6) 1.6(0.3-7.0) 1.2(0.2-6.6)
III 1.6*(1.3-1.9) 1.2(1.0-1.5) 1.1(0.3-3.6) 0.9(0.3-2.9)
IV 1.4*(1.1-1.7) 0.9(0.7-1.1) 1.2(0.4-3.9) 0.7(0.2-2.4)
Operation 1.1(0.9-1.3) 1.6*(1.3-1.9) 0.5(0.1-1.9) 0.6(0.1-2.2)
Chemotherapy 1.0(0.9-1.1) 1.2*(1.0-1.3) 1.3(0.8-2.4) 2.4*(1.4-4.4)
Radiation 1.0(0.9-1.2) 1.0(0.9-1.2) 0.9(0.6-1.3) 1.1(0.7-1.6)
Comorbidity
Diabetes 0.9(0.8-1.1) 0.9(0.8-1.0) 1.2(0.8-1.8) 1.1(0.7-1.7)
COPD 1.1(0.9-1.2) 1.0(0.9-1.2) 1.2(0.8-1.8) 1.1(0.7-1.7)
Renal disease 1.0(0.7-1.4) 0.9(0.7-1.2) 0.6(0.2-1.9) 0.4(0.1-1.6)
Pneumoconiosis 3.3*(2.0-5.6) 3.0*(1.8-5.1) 0.9(0.1-15.7) -
Hypertension 0.9(0.7-1.0) 0.8(0.7-1.0) 0.9(0.5-1.5) 0.9(0.5-1.5)
Dyslipidemia 0.6(0.4-1.1) 0.7(0.4-1.1) 1.9(0.6-5.7) 1.8(0.5-6.3)
Ischemic Heart Disease 0.9(0.6-1.2) 0.8(0.6-1.1) 0.7(0.3-2.0) 0.6(0.2-2.0)
Cerebrovascular Disease 1.1(0.7-1.7) 0.9(0.6-1.4) 0.3(<0.01-4.1) -
Smoking, yes 1.3*(1.1-1.5) 1.2(1.00-1.4) 1.1(0.5-2.5) 1.2(0.5-2.8)

1. The adjusted hazard ratio of PTB was derived from the subdistribution hazard ratio and competing mortality risk.

*. P-value less than 0.05.