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. 2023 Feb 8;32(1):25–45. doi: 10.7570/jomes22067

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Copyright © 2023 Korean Society for the Study of Obesity

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(A) Change in glycosylated hemoglobin (HbA1c) with different doses of tirzepatide and comparators in SURPASS programme. (B) Change in weight with different doses of tirzepatide and comparators in SURPASS programme and SURMOUNT-1 study. All data is presented as efficacy estimand. *P< 0.05 for the estimated treatment difference with each dose of tirzepatide vs. placebo and/or active comparator. T2DM, type 2 diabetes mellitus; Met, metformin; SGLT2i, sodium-glucose co-transporter 2 inhibitor; SU, sulfonylurea; OAD, oral antidiabetic drug; Tirz, tirzepatide; Pbo, placebo; Sema, semaglutide; Degl, insulin degludec; Glar, insulin glargine; Dula, dulaglutide.