Table 2.
Univariate and multivariate analysis of prognostic factors in 60 HGSOC specimens
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| OS | ||||
| Age | 1.919 (0.827 - 4.452) | 0.129 | ||
| Preoperative CA125 level | 2.176 (0.290 - 16.322) | 0.450 | ||
| Ascites | 1.115 (0.456 - 2.726) | 0.812 | ||
| Location | 1.635 (0.680 - 3.929) | 0.272 | ||
| FIGO stage | 8.188 (2.292 - 29.252) | 0.001 | 4.809 (1.226 - 18.869) | 0.024 |
| Residual disease | 2.260 (0.758 - 6.736) | 0.143 | ||
| Response to first line chemotherapy | 6.037 (2.573 - 14.163) | <0.001 | 3.061 (1.182 - 7.932) | 0.021 |
| DEPDC1B expression | 3.080 (1.337 - 7.098) | 0.008 | 2.778 (1.148 - 6.725) | 0.023 |
| PFS | ||||
| Age | 1.449 (0.760 - 2.765) | 0.260 | ||
| Preoperative CA125 level | 0.541 (0.165 - 1.775) | 0.311 | ||
| Ascites | 1.256 (0.638 - 2.472) | 0.510 | ||
| Location | 1.365 (0.686 - 2.713) | 0.375 | ||
| FIGO stage | 6.707 (2.325 - 19.354) | <0.001 | 4.712 (1.549 - 14.332) | 0.006 |
| Residual disease | 2.063 (0.902 - 4.717) | 0.086 | ||
| Response to first line chemotherapy | 60.355 (15.498 - 235.046) | <0.001 | 39.563 (9.750 - 160.539) | <0.001 |
| DEPDC1B expression | 2.249 (1.136 - 4.455) | 0.020 | 1.760 (0.845 - 3.669) | 0.131 |