. 2022 Feb 8;9(1):3–7. doi: 10.5152/eurjrheum.2020.21225
Content of this journal is licensed under a Table 1.
Clinical characteristics of three subgroups of patients with lupus in our cohort.
| All patients (n = 724) | Cluster 1 (n = 270) | Cluster 2 (n = 179) | Cluster 3 (n = 275) | P value | |
|---|---|---|---|---|---|
| Race/ethnicity | |||||
| White | 529 (73%) | 157 (58%) | 146 (82%) | 226 (82%) | 2.04 × 10−9 |
| Black | 168 (23%) | 98 (37%) | 29 (16%) | 41 (15%) | - |
| Asian | 16 (2%) | 9 (3%) | 3 (2%) | 4 (1%) | - |
| Other/not reported | 11 (<2%) | 6 (2%) | 1 (<1%) | 4 (1%) | |
| Sex | |||||
| Female | 672 (93%) | 242 (90%) | 166 (93%) | 264 (96%) | .0158 |
| Male | 52 (7%) | 28 (10%) | 13 (7%) | 11 (4%) | - |
| Manifestations | |||||
| Malar rash | 218 (30%) | 39 (14%) | 125 (70%) | 54 (20%) | 1.77 × 10−39 |
| Discoid rash | 95 (13%) | 48 (18%) | 18 (10%) | 29 (11%) | .0201 |
| Photosensitivity | 353 (49%) | 29 (11%) | 142 (79%) | 182 (66%) | 7.11 × 10−56 |
| Oral ulcers | 322 (44%) | 39 (14%) | 37 (21%) | 246 (89%) | 6.14 × 10−79 |
| Arthritis | 623 (86%) | 218 (81%) | 163 (91%) | 242 (88%) | .00574 |
| Serositis | 232 (32%) | 91 (34%) | 49 (27%) | 92 (33%) | .334 |
| Renal disorder | 119 (16%) | 82 (30%) | 19 (11%) | 18 (7%) | 5.79 × 10−14 |
| Neurologic disorder | 30 (4%) | 14 (5%) | 5 (3%) | 11 (4%) | .455 |
| Hematologic disorder | 277 (38%) | 204 (76%) | 19 (11%) | 54 (20%) | 7.11 × 10−56 |
| Immunologic disorder | 496 (69%) | 250 (93%) | 147 (82%) | 99 (36%) | 1.22 × 10−48 |
| Positive ANA | 674 (93%) | 262 (97%) | 160 (89%) | 252 (92%) | .00562 |