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Geometric mean anti-Sm-TSP-2 IgG subclass responses over time by vaccine group, as measured by ELISA (Arbitrary Units): A) IgG1, B) IgG3, C) IgG4. (Per-protocol immunogenicity population). Note: Vaccinations were administered on study days 1, 57, and 113. Error bars represent 95% confidence intervals. Euvax B hepatitis B recipients were pooled across cohorts.
