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. 2023 Apr 11;14:2048. doi: 10.1038/s41467-023-37541-6

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Rolling average (7-day) of daily new SARS-CoV-2 confirmed cases in Amazonas (solid line) and the number of SARS-CoV-2 genomes sequenced in this study (yellow bars) between 1st July 2021 and 31st January 2022. b Map of Amazonas state showing regions covered by the SARS-CoV-2 genomes generated in this study. Numbers represent genomes generated for each region. c Number of SARS-CoV-2 confirmed cases and SARS-CoV-2 genomes from different Amazonian regions between 1st July 2021 and 31st January 2022. d–e Frequency of VOCs Gamma, Delta, and Omicron BA.1 among SARS-CoV-2 positive samples sequenced in Amazonas since 1st July 2021 (d) or since the first detection of each viral variant (e). f Frequency of VOCs Delta and Omicron BA.1 among SARS-CoV-2 positive samples sequenced within and outside Manaus since the first detection of each viral variant. Amazonas’ map was generated with QGIS v.3.10.2 software (http://qgis.org) using public access data downloaded from the GADM v.3.6 database (https://gadm.org) and shapefiles obtained from the Brazilian Institute of Geography and Statistics (https://portaldemapas.ibge.gov.br/portal.php#homepage).