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. Author manuscript; available in PMC: 2023 Apr 11.
Published in final edited form as: Nature. 2022 Jun 22;606(7916):945–952. doi: 10.1038/s41586-022-04844-5

Extended Data Fig. 10. Phenotype of CD8 T cells from ALS4 patients and controls.

Extended Data Fig. 10.

a,b, UMAP projections of identified clusters showing differential expression of surface markers (by oligo-conjugated antibodies) (a) and of the top genes (b) in ALS4 versus control donors. c, Spectral flow cytometry analysis of the 6 samples used for CITE-seq. Histograms show the frequency of CCR7+ CD8 T cells and dot plots the proportion of the indicated subsets after gating on CCR7pos or neg CD8 T cells as indicated.