Table 3.
Comparison of Indian vaccines vs. other vaccines used globally in terms of storage feasibility and cost per dose
| Vaccine type | Manufacturer | Doses administer | Cold storage conditions | Cost per dose |
|---|---|---|---|---|
| BNT16b2 | Pfizer/BioNtech |
30 μg 2 doses 21 days interval |
− 80 °C to − 60 °C for long-term storage or at – 25 °C to – 15 °C for up to 2 weeks Vials prior to use may be stored at 4 °C refrigerator for up to 31 days or 2 h for room temperature |
EU and USA: $19.50 African Union: $6.75 Brazil: $10 Colombia: $12 |
| mRNA-1273 | Moderna |
100 μg 2 doses 28 days interval |
Long-term storage in frozen suspension stored between − 50 and – 15 °C. For short-term unopened vial storage at 4 °C refrigerator for up to 30 days. Room temperature for up to 24 h |
EU: $25.5 USA: $15 Argentina: $21.5 Botswana: $28.8 |
| AZD1222 ChAdOx1 nCoV-19 vaccine | AstraZeneca/University of Oxford |
5 × 1010 viral particles (standard dose) 2 doses 4- to 12-week interval |
Do not freeze. The unopened vial can be stored for up to 6 months. Short-term storage at 4 °C refrigerator after opening in a refrigerator for no more than 48 h. Storage at room temperature up to 6 h |
$2.15 in the EU $4–6 elsewhere |
| Ad26.COV2.S | Johnson & Johnson |
5 × 1010 viral particles A single dose |
Should be protected from light. Supplied as a liquid suspension Unopened vial can be stored at in 4 °C refrigerator until the expiration date or at room temperature for up to 12 h. After the first dose has been withdrawn, the vial is held between 4 °C refrigerator for up to 6 h or at room temperature for up to 2 h | < $10 |
| Gam-COVID-Vax Sputnik V | Gamaleya Research Institute |
1011 viral particles per dose for each recombinant adenovirus 0.5 mL/dose 2 doses 21 days interval |
Transport: two forms: lyophilized or frozen storage in 4 °C refrigerator | < $10 |
| NVX-CoV2373 | Novavax |
5 μg protein and 50 ug matrix-M adjuvant 2 doses 21 days interval |
Shipped in a ready-to-use liquid formulation storage in 4 °C refrigerator | $20.9 for Denmark COVAX: $3 |
| Convidecia™ Ad5-nCoV | CanSino |
1010 viral particles per 0.5 mL in a vial Single dose |
Do not freeze. Supplied as a vial of 0.5 mL. Storage in 4 °C refrigerator | Pakistan private market: $27.2 |
| CoronaVac | Sinovac Biotech |
3 μg 0.5 mL per dose 2 doses 28 days interval |
Supplied as a vial or syringe of 0.5 mL. Do not freeze. Protect from light Storage and transport in 4 °C refrigerator. Shake well before use Shelf-life: 12 months | China: $29.75 Ukraine: $18 Philippines: $14.5 Brazil: $10.3 Cambodia: $10 |
| BBIBP-COrV | Sinopharm/Beijing Institute of Biological Products |
4 μg 0.5 mL per dose Intramuscularly 2 doses 21- to 28-day interval |
Supplied as a pre-filled syringe or vial. Cannot be frozen. Protect from light. Store and transport in 4 °C refrigerator | Argentina, Mongolia: $15 Senegal: $18.6 China: $30 Hungary: $36 |
| Covaxin | Bharat Biotech |
6 μg single dose: 0.5 mL 10-dose or 20-dose vial Intramuscularly 2 doses 28 days interval |
Supplied as a single dose or multidose vial. Do not freeze. Stored in 4 °C refrigerator |
India: $3–5 Brazil: $15 Botswana: $16 |