1.
Results summary. Simulated BIVAT-90 (top section) and LVAT-95 (bottom section) during baseline, CRT, selective HBP (S-HBP) and LBBP (S-LBBP), HOT-CRT and LOT-CRT for different conduction disturbances.
| Biventricular response – BIVAT-90 | ||||||
|---|---|---|---|---|---|---|
| Baseline | CRT | S-HBP | S-LBBP | HOT-CRT | LOT-CRT | |
| LBBB | 87.6 ± 9.0 | 68.0 ± 8.0 | 42.6 ± 3.8 | 48.0 ± 5.3 | - | - |
| LBBB & moderately slow LV Purkinje | 98.0 ± 9.6 | 76.4 ± 8.3 | 49.1 ± 4.6 | 56.7 ± 6.5 | 45.9 ± 4.1 | 51.7 ± 5.3 |
| LBBB & severely slow LV Purkinje | 129.9 ± 11.8 | 93.0 ± 8.9 | 101.5 ± 7.8 | 89.1 ± 9.8 | 87.6 ± 6.7 | 73.9 ± 7.6 |
| LBBB & moderately slow myocardium | 107.2 ± 12.6 | 83.6 ± 11.8 | 54.7 ± 5.1 | 59.8 ± 6.3 | 52.5 ± 4.6 | 56.7 ± 5.5 |
| LBBB & severely slow myocardium | 172.7 ± 26.2 | 134.5 ± 24.1 | 97.1 ± 9.9 | 101.5 ± 10.7 | 94.6 ± 9.4 | 98.2 ± 10.0 |
| LBBB & septal scar | 119.1 ± 10.8 | 85.1 ± 9.8 | 117.2 ± 14.9 | 118.1 ± 12.9 | 94.5 ± 11.6 | 96.7 ± 13.0 |
| LBBB & LV lateral wall scar | 124.8 ± 13.2 | 119.0 ± 17.4 | 105.3 ± 12.8 | 102.6 ± 12.5 | 101.9 ± 12.3 | 99.5 ± 12.0 |
| Left ventricular response – LVAT-95 | ||||||
| LBBB | 94.8 ± 9.3 | 79.8 ± 7.7 | 51.2 ± 14.0 | 59.0 ± 6.5 | - | - |
| LBBB & moderately slow LV Purkinje | 106.7 ± 9.9 | 89.4 ± 8.2 | 59.4 ± 5.6 | 70.4 ± 7.4 | 53.2 ± 4.4 | 62.7 ± 5.9 |
| LBBB & severely slow LV Purkinje | 143.6 ± 11.7 | 108.5 ± 9.2 | 113.4 ± 8.7 | 108.7 ± 10.2 | 95.1 ± 7.6 | 89.9 ± 8.4 |
| LBBB & moderately slow myocardium | 116.4 ± 12.6 | 96.6 ± 10.4 | 65.5 ± 6.1 | 73.0 ± 7.8 | 61.0 ± 5.1 | 67.6 ± 6.5 |
| LBBB & severely slow myocardium | 189.6 ± 25.8 | 152.1 ± 21.7 | 115.0 ± 11.0 | 121.8 ± 12.5 | 109.2 ± 9.8 | 115.2 ± 10.8 |
| LBBB & septal scar | 130.9 ± 11.2 | 100.1 ± 9.5 | 129.4 ± 13.9 | 130.2 ± 11.6 | 101.7 ± 10.7 | 104.1 ± 13.6 |
| LBBB & LV lateral wall scar | 148.0 ± 15.2 | 142.2 ± 19.6 | 129.2 ± 14.1 | 125.4 ± 14.0 | 125.1 ± 14.1 | 122.0 ± 13.9 |