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. 2023 Apr 12;14(4):265. doi: 10.1038/s41419-023-05771-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — HepG2 and HuH7 cells were transfected with GRP75-plasmid in the presence or absence of XIAP-siRNA. A Western blot analysis of the expressions of GRP75, XIAP(p-S87), and XIAP. B Relative caspase-9/3 activities. C Flow cytometric analyses of the percentage of cells in apoptosis under the treatment of 10.0 μM cisplatin. D and E Cell viability was determined in triplicate, and the IC₅₀s were calculated.