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. 2023 Mar 29;14:1148255. doi: 10.3389/fmicb.2023.1148255

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Copyright © 2023 Facciuolo, Van Kessel, Kroeker, Liao, Lew, Falzarano, Kelvin, Gerdts and Napper.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Virus neutralizing and cross-neutralizing antibody responses. (A) Anti-SARS-CoV-2 neutralizing antibody titers for ancestral Wuhan strain, Delta, and Omicron in plasma at 2, 4, 6, and 12 months post-primary infection. (B) Anti-SARS-CoV-2 neutralizing antibody titers for ancestral Wuhan strain, Delta, and Omicron in plasma after reinfection at 2, 4, 6, and 12 months post-primary infection. Each dot represents the group median (n = 6 for 2-, 4- and 6 month time-points; n = 10 for 12 month time-point), error bars represent 95% confidence interval. P-values were calculated using a Kruskal-Wallis one-way ANOVA. **p < 0.05; ***p < 0.0001.