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Competing endogenous RNAs (CeRNAs) networks and mechanisms. CeRNAs link the function of protein-coding mRNAs with miRNAs, lncRNAs, circRNAs, and pseudogenic RNAs. CeRNAs target binding (sponge) MREs (pseudogene transcripts, lncRNA, miRNAs, and circRNA) to revive the inhibition of downstream target genes, and this regulatory mode constitutes the ceRNA mechanism.
