Table 3.
Microbial pathways showing a significant relationship with Tetratrichomonas abundance
| MetaCyc ID | Description | Log2 fold changea | Average abundance (CPM) | Species stratification | Stratified abundance | Adjusted P value |
|---|---|---|---|---|---|---|
| GLCMANNANAUT-PWY | Superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation | −1.28 | 5.19 | NA | 0.04 | |
| P441-PWY | Superpathway of N-acetylneuraminate degradation | −1.12 | 12.5 | NA | 0.03 | |
| PWY-6507 | 4-Deoxy-L-threo-hex-4-enopyranuronate degradation | −0.90 | 16.6 | NA | 0.03 | |
| PWY-7242 | D-fructuronate degradation | −0.76 | 25.4 | NA | 0.04 | |
| GALACTUROCAT-PWY | D-galacturonate degradation I | −0.73 | 21.9 | NA | 0.04 | |
| GALACT-GLUCUROCAT-PWY | Superpathway of hexuronide and hexuronate degradation | −0.65 | 25.7 | NA | 0.04 | |
| GLUCUROCAT-PWY | Superpathway of β-D-glucuronosides degradation | −0.61 | 27.1 | NA | 0.04 | |
| PWY-5686 | UMP biosynthesis | −0.44 | 38.7 | Treponema succinifaciens | 0.014 | 0.04 |
| Bifidobacterium angulatum | 0.018 | |||||
| Coprococcus catus | 0.050 | |||||
| Eubacterium biforme | 0.061 | |||||
| PWY-6386 | UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing) | −0.38 | 41.8 | Bifidobacterium angulatum | 0.0054 | 0.05 |
| Treponema succinifaciens | 0.023 | |||||
| Phascolarctobacterium succinatutens | 0.051 | |||||
| Eubacterium biforme | 0.070 | |||||
| PWY-6385 | Peptidoglycan biosynthesis III (mycobacteria) | −0.37 | 46.9 | Treponema succinifaciens | 0.024 | 0.04 |
| Phascolarctobacterium succinatutens | 0.130 | |||||
| PWY-6387 | UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) | −0.36 | 53.3 | Bifidobacterium angulatum | 0.0050 | 0.04 |
| Treponema succinifaciens | 0.021 | |||||
| Eubacterium biforme | 0.053 | |||||
| Phascolarctobacterium succinatutens | 0.130 | |||||
| PEPTIDOGLYCANSYN-PWY | Peptidoglycan biosynthesis I (meso-diaminopimelate containing) | −0.35 | 55.9 | Bifidobacterium angulatum | 0.0059 | 0.04 |
| Treponema succinifaciens | 0.024 | |||||
| Eubacterium biforme | 0.051 | |||||
| Phascolarctobacterium succinatutens | 0.13 | |||||
a
The coefficient resulting from the linear regression fit between pathway and Tetratrichomonas abundance, interpreted as the log2 fold change in pathway abundance per unit of Tetratrichomonas abundance.