Table 1.
Prevalence of HPV infection within various cervical histological diagnoses.
| Histology | Case# | Mean Age (ranges) | hrHPV | lrHPV+ | ||
|---|---|---|---|---|---|---|
| Case# | % | Case# | % | |||
| Negative | 46,440 | 43.0 (15-92) | 20,396 | 43.9 | 2682 | 5.8 |
| CIN1 | 10,058 | 39.1 (15-81) | 8,896 | 88.4 | 1465 | 14.6 |
| CIN2/3 | 3,773 | 42.7 (16-85) | 3,502 | 92.8 | 239 | 6.3 |
| SCC | 778 | 52.0 (22-84) | 729 | 93.7 | 32 | 4.1 |
| AIS | 57 | 39.6 (25-79) | 50 | 87.7 | 2 | 3.5 |
| ADC | 111 | 47.9 (18-82) | 78 | 70.3 | 1 | 0.9 |
| AIS+ CIN2/3 | 87 | 38.9 (21-70) | 80 | 92.0 | 5 | 5.7 |
| ADSQ | 101 | 48.6 (23-71) | 95 | 94.1 | 4 | 4.0 |
| SNEC | 17 | 43.4 (22-64) | 14 | 82.4 | 1 | 5.9 |
| Total | 61,422 | 42.5 (15-92) | 33,840 | 55.1 | 4431 | 7.2 |
CIN1, cervical intraepithelial neoplasia 1; CIN2/3, cervical intraepithelial neoplasia 2/3; AIS, endocervical adenocarcinoma in situ; SCC, squamous cell carcinoma of cervix, ADC, invasive adenocarcinoma of endocervix; ADSQ, adenosquamous carcinoma of endocervix; SNEC, small cell neuroendocrine carcinoma of endocervix; hrHPV, high risk human papillomavirus; lrHPV, low risk human papillomavirus; #, number.
18 genotypes of hrHPV, as detected by the BioPerfectus Multiplex Real-Time PCR assay in current study, include HPV-16, HPV-18, HPV-31, HPV-33, HPV-35, HPV-39, HPV-45, HPV-51, HPV-52, HPV-56, HPV-58, HPV-59, HPV-66, HPV-68, HPV-26, HPV-53, HPV-73, and HPV-82. Three genotypes of lrHPV, as detected by the BioPerfectus Multiplex Real-Time PCR assay, including HPV-6, HPV-11, and HPV-81.