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. 2023 Mar 29;13:1161631. doi: 10.3389/fonc.2023.1161631

Table 3.

Percentage of multiple hrHPV infection among hrHPV-positive cases within various histological groups.

Histology <30 y 30-49 y ≥50 y Total
hrHPV Positive# 2≥hrHPV#
(%)
hrHPV Positive# ≥2 hrHPV#
(%)
hrHPV Positive# ≥2 hrHPV#
(%)
hrHPV Positive# ≥2 hrHPV#
(%)
Negative 3,422 1040 (30.4) 11,040 2,412 (21.8) 5,934 1760 (29.7) 20,396 5212 (25.6)
CIN1 2,174 1063 (48.9) 4,909 1,764 (35.9) 1813 845 (46.6) 8,896 3672 (41.3)
CIN2/3 481 191 (39.7) 2,040 634 (31.1) 981 376 (38.3) 3,502 1201 (34.3)
SCC 12 2 (16.7) 269 52 (19.3) 448 116 (25.9) 729 170 (23.3)
AIS 5 0 (0.0) 39 5 (12.8) 6 0 (0.0) 50 5 (10.0)
ADC 3 2 (66.7) 47 12 (25.5) 28 7 (25.0) 78 21 (26.9)
AIS+HSIL 18 5 (27.8) 48 12 (25.0) 14 3 (21.4) 80 20 (25.0)
ADSQ 6 1 (16.7) 41 3 (7.3) 48 12 (25.0) 95 16 (16.8)
SNEC 2 1 (50.0) 9 4 (44.4) 3 0 (0.0) 14 5 (35.7)

CIN1, cervical intraepithelial neoplasia 1; CIN2/3, cervical intraepithelial neoplasia 2/3; AIS, endocervical adenocarcinoma in situ; SCC, squamous cell carcinoma of cervix, ADC, invasive adenocarcinoma of endocervix; ADSQ, adenosquamous carcinoma of endocervix; SNEC, small cell neuroendocrine carcinoma of endocervix; hrHPV, high-risk human papillomavirus; #, number; y, years.