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. 2023 Mar 29;14:1101564. doi: 10.3389/fimmu.2023.1101564

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Copyright © 2023 Li, Liu, Wang, Wang, Zhu, Tang, Wang, Zhou, Gao and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Detection of biomarkers of the AIS A and AIS D grades of SCI. (A) Expression of biomarkers between different grades of SCI and HC groups in the dataset. (B) Validation of the diagnostic value of biomarkers. (C) Expression levels of biomarkers detected by qPCR. Values are expressed as the means ± SEM. n = 3 for each group. Student’s t-test was used. ***P < 0.001; **P < 0.01; *P < 0.05; ns, no significance. A P value < 0.05 was regarded as statistically significant. SCI, spinal cord injury; HC, healthy uninjured control; TC, trauma control with noncentral nervous system injury; AIS, American Spinal Cord Injury Association Impairment Scale; AUC, area under the curve; qPCR, quantitative polymerase chain reaction.