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Volcano plots for ∼20-year risk of diabetes and scatterplot comparing discovery and validation: the ARIC study. Estimates adjusted for age, sex, race-center, eGFR, smoking status, physical activity, total cholesterol, HDL-cholesterol, systolic blood pressure, hypertension medication use, and BMI. Bonferroni-corrected P value in discovery based on P < 0.05/4,955.
