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. 2023 Feb 7;10(1):35–51. doi: 10.3934/publichealth.2023004

Table 1. Summary of evidence for treatment of ADHD core symptoms.

Single modalities Combinations

Type of treatment Effective outcomes Mixed/Non-effective outcomes Effectiveness
Behavioural therapy (BT) Moderate ES for typically unblinded parent ratings [20]. Effect size near 0 and non-significant for probably blinded measurements [20]. BT and stimulants: superior to stimulants or non-stimulants [5].
Computer-based Cognitive training (CT) CT game for attention: reduction in the clinician ADHD-RS and functional EEG changes [31].
All types of CT: Significant effects on total ADHD ([SMD] = 0.37) and inattentive symptoms (SMD = 0.47) for unblinded raters [33].
CT for working memory: either no effect or mixed effects on ADHD symptoms [15],[32].
All types of CT: Small ES for total ADHD symptoms ([SMD] = 0.2) and inattentive symptoms (SMD = 0.32) for blinded raters [33].
All types of CT: No significant effects on H/I symptoms [33].
Stimulants and combined treatment groups with CT: More effective in improving ADHD symptoms [32].
Cognitive Behaviour Therapy (CBT) Group-based CBT: Mixed effects on ADHD symptoms and functional impairment [34]. CBT and stimulants: improve core ADHD symptoms [17].
NeuroFeedback [NF] Medium to large ES on inattention [SMD = 0.64 to 0.80), while ES for H/I was medium [SMD = 0.50–0.61) [35]. Effect is mixed for core ADHD symptoms, academic & social skills [36][38].
Psychoeducation Parents group Psychoeducation: Significant reduction of ADHD symptoms (p = 0.001) [18].
Meditation Low to moderate efficacy (Hedge's g = −0.44, 95% CI −0.69 to −0.19, I20%) compared to control conditions [19].

*Note: BT – Behavioural therapy; CT – Computer-based Training; ES – Effect size (measured by SMD); H/I – Hyperactivity/Impulsivity symptoms; SMD – Standardized Mean Difference.