Table III.

Multivariate analysis for overall survival.

Characteristic	Regression coefficient	P-value	HR (95% CI)
PS (≥2 vs. 0–1)	0.4860	0.016	1.63 (1.10–2.41)
NG (3 vs. 1–2)	0.7776	0.002	2.18 (1.34–3.53)
Previous systemic therapy (yes vs. no)	0.4543	0.038	1.58 (1.03–2.42)
Brain metastases (yes vs. no)	0.6747	0.046	1.96 (1.01–3.81)
Liver metastases (yes vs. no)	0.5621	0.006	1.75 (1.17–2.63)
Lung metastases (yes vs. no)	0.1131	0.627	1.12 (0.71–1.77)

HR, hazard ratio; CI, confidence interval; PS, Eastern Cooperative Oncology Group performance status; NG, nuclear grade.