Table 1.
Demographic and clinical information by group.
| HC (n = 236) |
CHR (n = 552) |
CHR | ||
|---|---|---|---|---|
| CHR-NC (n = 225) |
CHR-C (n = 73) |
|||
| Age (years, mean ± SD)a | 20.44 ± 4.72 | 19.21 ± 4.38 | 19.39 ± 4.59 | 18.49 ± 3.64 |
| Sex, N (percentage) | ||||
| Female | 111 (47.0) | 236 (42.8) | 104 (46.2) | 27 (37.0) |
| Male | 125 (53.0) | 316 (57.2) | 121 (53.8) | 46 (63.0) |
| Education (years, mean ± SD)b | 12.8(3.6) | 11.3(2.8) | 11.3(2.7) | 11.0(2.7) |
| Income bracket (mean ± SD) | 4.1(1.7) | 4.1(1.7) | 4.1(1.6) | 4.2(1.7) |
| SOPS (mean ± SD) | ||||
| Positive symptomsc | 0.90 ± 1.50 | 11.42 ± 4.16 | 10.88 ± 4.41 | 13.19 ± 4.02 |
| Negative symptomsd | 1.53 ± 2.47 | 11.49 ± 6.16 | 11.14 ± 6.30 | 12.27 ± 6.33 |
| Disorganizatione | 0.65 ± 1.18 | 4.98 ± 3.06 | 4.70 ± 3.10 | 6.12 ± 3.97 |
| General symptomsf | 1.31 ± 2.12 | 8.77 ± 4.35 | 7.99 ± 4.34 | 9.53 ± 4.33 |
HC = Healthy control subjects; CHR = Clinical High Risk subjects (at Baseline).
CHR-NC = Subjects who did not converted to psychosis by 2 years.
CHR-C = Subjects who converted to psychosis by 2 years; SOPS = Scale of Prodromal Symptoms.
a
HC > CHR (p < 0.001); HC > CHR_NC (p = 0.013); HC > CHR_C (p = 0.001).
b
HC > CHR (p < 0.001); HC > CHR_NC (p < 0.001); HC > CHR_C (p < 0.001).
c
HC < CHR (p < 0.001); HC < CHR_NC < CHR_C (p < 0.001).
d
HC < CHR (p < 0.001); HC < CHR_NC (p < 0.001); HC < CHR_C (p < 0.001).
e
HC < CHR (p < 0.001); HC < CHR_NC < CHR_C (p < 0.001).
f
HC < CHR (p < 0.001); HC < CHR_NC < CHR_C (p ≤ 0.001).