Table 2.
Comparison of left heart structure and function between PLWHA and controls.
| PLWHA (n = 105) | Controls (n = 90) | p‐Value | ||
|---|---|---|---|---|
| Cardiac structure | IVST (mm) | 9.0 (7.5–10.0) | 8.0 (7.0–9.0) | .070 |
| LVPWT (mm) | 9.0 (8.0–10.0) | 9.0 (8.0–10.0) | .431 | |
| LAD (mm) | 35.08 ± 3.62 | 34.42 ± 3.64 | .212 | |
| LVEDD (mm) | 48.53 ± 4.47 | 46.25 ± 3.45 | .026* | |
| LVESD (mm) | 29.32 ± 3.68 | 28.50 ± 3.06 | .094 | |
| LVMI (g/m2) | 83 (75–94) | 79 (73–85) | .007** | |
| LAVI (mL/m2) | 32.33 ± 5.93 | 30.67 ± 5.01 | .037* | |
| LVEDV (mL) | 110 (92–123) | 103 (86–115) | .020* | |
| LVEDI (mL/m2) | 65 ± 12 | 61 ± 9 | .017* | |
| Systolic function | LVEF (%) | 66.34 ± 5.68 | 67.64 ± 5.31 | .102 |
| LVFS (%) | 37.02 ± 4.82 | 37.74 ± 4.53 | .283 | |
| Mitral E/A ratio | 0.99 ± 0.28 | 1.13 ± 0.30 | .001** | |
| Septal e′ velocity (cm/s) | 8.14 ± 1.99 | 8.61 ± 1.97 | .103 | |
| Lateral e′ velocity(cm/s) | 10.29 ± 1.37 | 11.21 ± 2.62 | .002** | |
| Average E/e′ ratio | 9.30 ± 2.70 | 8.36 ± 3.21 | .028* | |
| Mitral DT (ms) | 203 (189–222) | 221 (200–231) | .001** |
Note: *p < .05; **p < .01.
Abbreviations: DT, deceleration time; E/A, ratio of early‐diastolic LV inflow velocity (E) to atrial‐systolic velocity (A); E/e′, ratio of early‐diastolic LV inflow velocity (E) to early‐diastolic mitral annular velocity (e′); e’, early‐diastolic mitral annular velocity; IVST, interventricular septum thickness; LAD, left atrium diameter; LAVI, left atrial volume index; LVEDD, left ventricular end‐diastolic diameter; LVEDI, left ventricular end diastolic volume index; LVEDV, left ventricular end diastolic volume; LVEF, left ventricular ejection fraction; LVESD, left ventricular end‐systolic diameter; LVFS, left ventricular fractional shortening; LVMI, left ventricular mass index; LVPW, left ventricular posterior wall thickness; PLWHA, patients living with HIV/AIDS.