Table 3.
Comparison of left heart structure and function between AIDS and HIV+ groups.
| AIDS (n = 37) | HIV+ (n = 68) | p‐Value | ||
|---|---|---|---|---|
| Cardiac structure | IVST (mm) | 9.0 (8.0–10.0) | 8.5 (7.0–9.8) | .173 |
| LVPWT (mm) | 10.0 (9.0–10.0) | 9.0 (8.0–10.0) | .252 | |
| LAD (mm) | 35.05 ± 4.12 | 35.09 ± 3.35 | .963 | |
| LVEDD (mm) | 49.14 ± 4.70 | 48.21 ± 4.35 | .312 | |
| LVESD (mm) | 28.86 ± 4.06 | 29.57 ± 3.46 | .348 | |
| LVMI (g/m2) | 88 (75–101) | 82 (75–90) | .189 | |
| LAVI (mL/m2) | 32.76 ± 5.94 | 32.10 ± 5.96 | .592 | |
| LVEDV (mL) | 114 (105‐127) | 108 (86‐123) | .053 | |
| LVEDI (mL/m2) | 69 ± 12 | 62 ± 11 | .007** | |
| Systolic function | LVEF (%) | 65.16 ± 5.80 | 67.00 ± 5.55 | .117 |
| LVFS (%) | 36.95 ± 4.96 | 37.06 ± 4.79 | .909 | |
| Mitral E/A ratio | 0.90 ± 0.30 | 1.03 ± 0.26 | .027* | |
| Septal e′ velocity (cm/s) | 7.91 ± 2.06 | 8.26 ± 1.96 | .391 | |
| Lateral e′ velocity(cm/s) | 9.95 ± 1.28 | 10.48 ± 1.39 | .057 | |
| Average E/e′ ratio | 10.32 ± 2.48 | 9.02 ± 2.49 | .012* | |
| Mitral DT (ms) | 194 (187–224) | 206 (189–220) | .589 |
Note: *p < .05; **p < .01.
Abbreviations: AIDS, acquired immune deficiency syndrome; DT, deceleration time; E/A, ratio of early‐diastolic LV inflow velocity (E) to atrial‐systolic velocity (A); E/e′, ratio of early‐diastolic LV inflow velocity (E) to early‐diastolic mitral annular velocity (e′); e′, early‐diastolic mitral annular velocity; HIV, human immunodeficiency virus; IVST, interventricular septum thickness; LAD, left atrium diameter; LAVI, left atrial volume index; LVEDD, left ventricular end‐diastolic diameter; LVEDI, left ventricular end diastolic volume index; LVEDV, left ventricular end diastolic volume; LVEF, left ventricular ejection fraction; LVESD, left ventricular end‐systolic diameter; LVFS, left ventricular fractional shortening; LVMI, left ventricular mass index; LVPW, left ventricular posterior wall thickness.