Table 5.
Logistic regression analysis of risk factors associated with LVDD in PLWHA.
| Variable | Univariate | Multivariate | ||
|---|---|---|---|---|
| Odds ratio (OR) (95% confidence interval [CI]) | p‐Value | OR (95% CI) | p‐Value | |
| Age (per 10‐year increase) | 1.839 (1.186–2.849) | .006* | 1.781 (1.076–2.947) | .025* |
| Body mass index | 1.249 (1.058–1.475) | .009* | 1.228 (1.016–1.485) | .033* |
| Hypertension | 3.537 (0.942–13.282) | .061** | 3.427 (0.805–14.583) | .096 |
| Diabetes | 1.697 (0.413–6.968) | .463 | ‐ | ‐ |
| Smoking history | 1.323 (0.566–3.092) | .518 | ‐ | ‐ |
| Duration of HIV infection (months) | 1.056 (0.963–1.159) | .244 | ‐ | ‐ |
| TC (mmol/L) | 1.135 (0.771–1.672) | .522 | ‐ | ‐ |
| TG (mmol/L) | 1.451 (0.948–2.220) | .087** | 1.067 (0.616–1.847) | .817 |
| LDL (mmol/L) | 1.517 (0.835–2.757) | .172 | ‐ | ‐ |
| HDL (mmol/L) | 0.203 (0.056–0.739) | .016* | 0.263 (0.048–1.441) | .124 |
| Viral load (log‐transformed) | 1.202 (0.854–1.692) | .291 | ‐ | ‐ |
| CD4+ Count 200 cells/μL | 3.111 (1.279–7.567) | .012* | 3.683 (1.357–9.995) | .010* |
Note: *p < .05; **p < .01. Variables with p < .1 in the univariate analysis were included in the multivariate logistic regression model.
Abbreviations: HDL‐C, high‐density lipoprotein cholesterol; LDL‐C, low‐density lipoprotein cholesterol; LVDD, left ventricular diastolic dysfunction; PLWHA, patients living with HIV/AIDS; TC, total cholesterol; TG, triglycerides.