TABLE 4.

Overview of reported myelin bilayer signal components (ex vivo)

Origin	Sample	Lineshape model	Component values	Component description	Reference
Human	Brain WM	Super‐Lorentzian	T2,min,U = 5.48 μs T2,min,S = 102 μs δU = 1.07 ppm δS = 2.09 ppm	U: Myelin S: Residual non‐aqueous content	Current study
Porcine	Brain WM	Super‐Lorentzian	T2,min,U = 7.5 μs T2,min,S = 101 μs δU = 1.38 ppm δS = 1.91 ppm	U: Myelin S: Residual non‐aqueous content	Weiger et al. 13
Bovine	Myelin lipid extract	Super‐Lorentzian	T2,min = 8 μs δ = 1.5 ppm	Methylene, shortest and largest (74% of total myelin signal)	Wilhelm et al. 12
Ovine	Cervical spinal cord	Super‐Lorentzian	T2,min = 10 μs	Methylene frequency, shortest and largest	Seifert et al. 21
Bovine	Brain WM	Super‐Lorentzian (Gaussian‐based)	σmin,U = 7.2 μs σmin,S = 87 μs δU = δS = 1.3 ppm	U: Shortest and largest S: Remaining	Manning et al. 27
Rat	Optic nerve	Lorentzian	T2 = 80 μs	Shortest and largest	Horch et al. 26

Note: Lorentzian‐based super‐Lorentzian components are characterized (in the time‐domain) by decay constant T_2,min, while Gaussian‐based super‐Lorentzian components are characterized (in the time‐domain) by the SD of the narrowest (i.e., shortest) constituent Gaussian, σ_min. In studies in which multiple values were provided for the same parameter, the mean value is given. δ denotes the component chemical shift, which was calibrated with water at 4.7 ppm.