Comparison 31. SE ‐ Constipation.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Paroxetine versus older ADs	26	3934	Odds Ratio (M‐H, Random, 95% CI)	0.49 [0.40, 0.60]
1.1 versus amitriptyline	10	1146	Odds Ratio (M‐H, Random, 95% CI)	0.61 [0.37, 0.99]
1.2 versus clomipramine	2	1111	Odds Ratio (M‐H, Random, 95% CI)	0.57 [0.38, 0.85]
1.3 versus dothiepin	1	271	Odds Ratio (M‐H, Random, 95% CI)	0.57 [0.32, 0.99]
1.4 versus imipramine	7	633	Odds Ratio (M‐H, Random, 95% CI)	0.40 [0.25, 0.63]
1.5 versus lofepramine	2	228	Odds Ratio (M‐H, Random, 95% CI)	0.49 [0.20, 1.23]
1.6 versus maprolitine	3	429	Odds Ratio (M‐H, Random, 95% CI)	0.31 [0.17, 0.55]
1.7 versus mianserin	1	116	Odds Ratio (M‐H, Random, 95% CI)	0.22 [0.01, 4.73]
2 Paroxetine versus other SSRIs	7		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
2.1 versus escitalopram	1	454	Odds Ratio (M‐H, Random, 95% CI)	2.52 [0.87, 7.29]
2.2 versus fluoxetine	3	1001	Odds Ratio (M‐H, Random, 95% CI)	2.71 [1.47, 5.01]
2.3 versus fluvoxamine	1	60	Odds Ratio (M‐H, Random, 95% CI)	2.15 [0.36, 12.76]
2.4 versus sertraline	2	545	Odds Ratio (M‐H, Random, 95% CI)	3.26 [1.73, 6.14]
3 Paroxetine versus newer or non‐conventional ADs	16		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
3.1 versus bupropion	2	240	Odds Ratio (M‐H, Random, 95% CI)	2.00 [0.59, 6.81]
3.2 versus duloxetine	5	1573	Odds Ratio (M‐H, Random, 95% CI)	0.74 [0.46, 1.18]
3.3 versus mirtazapine	2	529	Odds Ratio (M‐H, Random, 95% CI)	0.93 [0.51, 1.69]
3.4 versus nefazodone	1	40	Odds Ratio (M‐H, Random, 95% CI)	3.35 [0.32, 35.36]
3.5 versus reboxetine	3	1375	Odds Ratio (M‐H, Random, 95% CI)	0.48 [0.36, 0.63]
3.6 versus tianeptine	1	277	Odds Ratio (M‐H, Random, 95% CI)	7.10 [0.36, 138.80]
3.7 versus venlafaxine	2	466	Odds Ratio (M‐H, Random, 95% CI)	1.16 [0.33, 4.12]