Comparison 35. SE ‐ Depression.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Paroxetine versus older ADs	2	323	Odds Ratio (M‐H, Random, 95% CI)	0.92 [0.09, 9.38]
1.1 versus amitriptyline	1	217	Odds Ratio (M‐H, Random, 95% CI)	3.0 [0.12, 74.46]
1.2 versus lofepramine	1	106	Odds Ratio (M‐H, Random, 95% CI)	0.28 [0.01, 7.06]
2 Paroxetine versus other SSRIs	4		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
2.1 versus fluoxetine	4	1128	Odds Ratio (M‐H, Random, 95% CI)	0.97 [0.45, 2.09]
3 Paroxetine versus newer or non‐conventional ADs	3		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
3.1 versus agomelatine	1	284	Odds Ratio (M‐H, Random, 95% CI)	1.41 [0.39, 5.13]
3.2 versus reboxetine	2	1050	Odds Ratio (M‐H, Random, 95% CI)	0.76 [0.23, 2.46]