Comparison 76. SE ‐ Sexual problems.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Anorgasmia	7		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 versus duloxetine	2	538	Odds Ratio (M‐H, Random, 95% CI)	0.69 [0.22, 2.18]
1.2 versus reboxetine	3	1375	Odds Ratio (M‐H, Random, 95% CI)	9.84 [2.23, 43.46]
1.3 versus sertraline	2	545	Odds Ratio (M‐H, Random, 95% CI)	2.22 [0.43, 11.36]
2 Ejaculation disorder	11		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
2.1 versus aprepitant (MK‐869)	1	143	Odds Ratio (M‐H, Random, 95% CI)	8.33 [1.82, 38.16]
2.2 versus fluoxetine	1	708	Odds Ratio (M‐H, Random, 95% CI)	3.17 [1.62, 6.20]
2.3 versus fluvoxamine	1	60	Odds Ratio (M‐H, Random, 95% CI)	3.22 [0.32, 32.89]
2.4 versus imipramine	1	79	Odds Ratio (M‐H, Random, 95% CI)	12.24 [0.65, 229.29]
2.5 versus maprolitine	1	71	Odds Ratio (M‐H, Random, 95% CI)	2.84 [0.11, 71.99]
2.6 versus reboxetine	3	1375	Odds Ratio (M‐H, Random, 95% CI)	0.73 [0.37, 1.46]
2.7 versus sertraline	2	545	Odds Ratio (M‐H, Random, 95% CI)	3.49 [1.67, 7.26]
2.8 versus tianeptine	1	277	Odds Ratio (M‐H, Random, 95% CI)	3.0 [0.12, 74.28]
3 Impotence	6		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
3.1 versus aprepitant (MK‐869)	1	143	Odds Ratio (M‐H, Random, 95% CI)	3.72 [0.74, 18.54]
3.2 versus duloxetine	1	264	Odds Ratio (M‐H, Random, 95% CI)	1.02 [0.25, 4.17]
3.3 versus fluvoxamine	1	60	Odds Ratio (M‐H, Random, 95% CI)	1.56 [0.24, 10.05]
3.4 versus reboxetine	3	1375	Odds Ratio (M‐H, Random, 95% CI)	0.60 [0.30, 1.17]
4 Libido decreased	11		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
4.1 versus aprepitant (MK‐869)	1	143	Odds Ratio (M‐H, Random, 95% CI)	9.39 [0.50, 177.78]
4.2 versus bupropion	1	140	Odds Ratio (M‐H, Random, 95% CI)	1.93 [0.67, 5.53]
4.3 versus duloxetine	3	802	Odds Ratio (M‐H, Random, 95% CI)	1.36 [0.36, 5.14]
4.4 versus fluvoxamine	1	60	Odds Ratio (M‐H, Random, 95% CI)	1.3 [0.31, 5.40]
4.5 versus maprotiline	1	298	Odds Ratio (M‐H, Random, 95% CI)	5.35 [0.25, 112.36]
4.6 versus reboxetine	3	1375	Odds Ratio (M‐H, Random, 95% CI)	2.34 [1.14, 4.82]
4.7 versus tianeptine	1	277	Odds Ratio (M‐H, Random, 95% CI)	0.99 [0.06, 16.03]
5 Penis disorder	1		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
5.1 versus reboxetine	1	530	Odds Ratio (M‐H, Random, 95% CI)	0.14 [0.01, 2.75]
6 NOS	14		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
6.1 versus amitriptyline	1	21	Odds Ratio (M‐H, Random, 95% CI)	2.0 [0.15, 26.19]
6.2 versus aprepitant (MK‐869)	1	143	Odds Ratio (M‐H, Random, 95% CI)	11.65 [0.63, 214.77]
6.3 versus bupropion	1	140	Odds Ratio (M‐H, Random, 95% CI)	2.35 [0.77, 7.15]
6.4 versus citalopram	1	406	Odds Ratio (M‐H, Random, 95% CI)	0.87 [0.38, 2.00]
6.5 versus clomipramine	1	1019	Odds Ratio (M‐H, Random, 95% CI)	1.60 [0.72, 3.55]
6.6 versus duloxetine	2	528	Odds Ratio (M‐H, Random, 95% CI)	1.25 [0.40, 3.90]
6.7 versus fluvoxamine	1	81	Odds Ratio (M‐H, Random, 95% CI)	1.36 [0.39, 4.70]
6.8 versus mirtazapine	1	275	Odds Ratio (M‐H, Random, 95% CI)	5.15 [1.69, 15.64]
6.9 versus nefazodone	1	40	Odds Ratio (M‐H, Random, 95% CI)	14.55 [0.75, 283.37]
6.10 versus nortriptyline	1	80	Odds Ratio (M‐H, Random, 95% CI)	2.65 [0.10, 66.96]
6.11 versus reboxetine	2	1050	Odds Ratio (M‐H, Random, 95% CI)	1.95 [0.48, 7.98]
6.12 versus venlafaxine	1	361	Odds Ratio (M‐H, Random, 95% CI)	1.29 [0.34, 4.90]