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. 2022 Nov 2;100(7):1252–1260. doi: 10.1002/ccd.30455

Table 1.

Summary of globally reported ex‐situ coronary angiography cases including our institutional experience

Case Donor age (years) Sex BMI (kg/m2) Smoker Diabetes HTN HL Functional WIT (min) Asystolic WIT (min) Time on OCS (min) Fluoro time (s) Angiographic findings Outcome
Case series
1 49 M 26.3 Yes No Yes No NR NR 319 438 Severe multivessel disease Unsuitable (DBD research run)
2 58 M 25.7 No No No Yes NR NR 265 NR Mild (<30%) atherosclerosis Transplanted (DBD)
3 54 M 32 No No Yes Yes 21 14 276 259 Mild (<30%) atherosclerosis Transplanted
4 51 M 29.4 No No Yes Yes 26 14 205 535 Mild (<30%) atherosclerosis Unsuitable on clinical grounds
5 53 F 26 No No No Yes 23 11 241 NR Minimal (<10%) atherosclerosis; separate origins of the LAD and LCx Transplanted
6 49 M 29.4 Yes No Yes No 13 10 296 135 Mild (<30%) atherosclerosis Transplanted
7 42 M 29.4 Yes No No No 21 14 160 186 Mild (<30%) atherosclerosis Transplanted
8 53 F 46.1 Yes Yes Yes Yes 24 14 285 216 Mild (<30%) atherosclerosis Transplanted
Literature search
Shibilsky et al. 10 NA NR Porcine model—moderate LAD stenosis; IVUS feasible NA
Ghodisizad et al. 8 46 M 24 NR 37 570 NR Minor diffuse atherosclerosis Unsuitable due to haemodynamic parameters

Note: aWIT is the time from cessation of circulation in the donor to delivery of preservation flush to the donor heart, >15 min is a predictor for severe primary graft dysfunction and perioperative ECMO. Functional WIT, functional warm ischemic time is the time from systolic of <90 mmHg in the donor to delivery of preservation flush to the donor heart, an upper limit of 30 min is permitted for this timeframe.

Abbreviations: CVD, cardiovascular disease; ECMO, extra corporeal membrane oxygenation; HL, hyperlipidaemia; HTN, hypertension; IVUS, intravascular ultrasound; LAD, left anterior descending artery; LCx, left circumflex coronary artery; OCS, organ care system; NR, not reported/recorded.