TABLE 5.
Some key outcomes from the 12‐week chronic RCT in the RESET study comparing dairy foods with a proportion of SFA replaced with monounsaturated fatty acids (Modified) with conventional dairy foods (Control) from Vasilopoulou et al. (2020)
| Modified dairy foods | Control dairy foods | p | |
|---|---|---|---|
| ∆ from baseline | ∆ from baseline | ||
| Fasting serum cholesterol | |||
| TC (mmol/L) | 0.12 ± 0.07 | 0.29 ± 0.06 | 0.08 |
| LDL‐C (mmol/L) | 0.03 ± 0.06 | 0.19 ± 0.05 | 0.03 |
| HDL‐C (mmol/L) | 0.04 ± 0.02 | 0.07 ± 0.02 | 0.55 |
| LDL‐C:HDL‐C ratio | −0.06 ± 0.04 | 0.05 ± 0.04 | 0.04 |
| TC:HDL‐C ratio | −0.03 ± 0.05 | −0.04 ± 0.03 | 0.13 |
| Endothelial function | |||
| % FMD | 0.35 ± 0.06 | −0.51 ± 0.15 | <0.0001 |
| Pre‐occlusion artery diameter (mm) | 0.06 ± 0.04 | 0.04 ± 0.04 | 0.08 |
| Peak artery diameter (mm) | 0.07 ± 0.04 | −0.07 ± 0.04 | 0.02 |
| Time to peak diameter (s) | −0.5 ± 1.9 | 4.5 ± 2.4 | 0.04 |
| CBEAI | |||
| Nitrite (μmol/L) | 0.02 ± 0.01 | −0.03 ± 0.02 | 0.01 |
| VCAM‐1 (ng/ml) | 3.0 ± 20.7 | 40.1 ± 1.7 | 0.08 |
Note: Values are unadjusted means ± SEM.
Abbreviations: CBEAI, circulating biomarkers of endothelial activation and inflammation; FMD, flow‐mediated dilatation; HDL‐C, high‐density lipoprotein cholesterol; LDL‐C, low‐density lipoprotein cholesterol; RCT, randomised controlled trial; TC, total cholesterol; VCAM‐1, vascular cell adhesion protein 1; ∆, change.