Figure 3.

Proportion of participants with AD achieving ≥ 4‐grade reduction from baseline in PP‐NRS at week 6 among participants with grade ≥ 4 at baseline. ^aAnalysis by exact Chan and Zhang method ⁴⁶ on the full analysis set using nonresponder imputation. Unadjusted, one‐sided P‐values: *P < 0·05 vs. respective vehicle. ^aProportion calculated based on the number of participants with PP‐NRS grade ≥ 4 at baseline. AD, atopic dermatitis; BID, twice daily; CI, confidence interval; PP‐NRS, peak pruritus numerical rating scale; QD, once daily. [Colour figure can be viewed at wileyonlinelibrary.com]