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. 2022 Oct 5;62(12):2555–2567. doi: 10.1111/trf.17127

TABLE 4.

RDS‐adjusted rate ratios (aRR) of recent HIV seroconversions (n = 31) for selected factors a among HIV‐negative participants, controlling for age and city (n = 2008)

HIV seroconversions aRR 95% CI
Models with a single risk factor
Sociodemographics
Age <30 years old 22 9.5 [3.3;26.9]
French or English Canadian ethnocultural group 14 0.5 [0.2;1.1]
Born outside of Canada 11 1.5 [0.7;3.1]
Immigrated to Canada in the past two years b 1
High school degree or less 6 1.0 [0.4;2.7]
Annual income <30 K 17 0.7 [0.3;1.4]
Financial strain (current) a 1.7 [0.9;3.2]
Gay (vs. queer or other sexual orientation) 28 1.2 [0.5;2.9]
Sex partners (past 6 months)
No main sex partner 25 3.2 [1.2;8.3]
Non monogamous relationship b 31
New anal sex partner 13 1.0 [0.5;2.0]
One or more HIV+ sex partners 19 3.9 [1.8;8.3]
Number of sex partners
  • 6 to 10 (vs. 5 or less)

9 4.4 [1.7;11.4]
  • 11 or more (vs. 5 or less)

19 7.4 [3.0;18.2]
Number of anal sex partners
  • 6 to 10 (vs. 5 or less)

10 5.4 [2.2;13.4]
  • 11 or more (vs. 5 or less)

15 10.5 [4.5;24.6]
Two or more anal sex partners b 30
Methods of finding sexual partners (past 6 months)
Attendance of a bath house or sex club 17 2.5 [1.2;5.3]
Attendance of a group sex event 15 3.4 [1.6;7.3]
Attendance of a barebacking party 10 9.2 [3.9;21.8]
Attendance of a party n’ play event 10 6.3 [2.1;19.3]
Accepting money or drugs for sex 9 3.7 [1.4;10.0]
Use of the internet to connect with other men (at least once a day) 18 6.8 [2.9;15.7]
Substance use (past 6 months)
Crystal methamphetamine during sex c 11 8.0 [3.1;20.8]
Gamma hydroxybutyrate during sex c 8 4.1 [1.5;11.1]
Alkyl nitrites during sex c 17 3.8 [1.8;8.1]
Chemsex d 13 4.0 [1.7;9.1]
Injection drug use (IDU) 5 9.8 [2.9;33.0]
Problematic alcohol use b 2
Problematic use of any drug (other than alcohol or tobacco) 5 1.7 [0.5;6.0]
STBBI detected (at any visit)
C. trachomatis infection 5 5.9 [2.2;15.6]
N. gonorrhoeae infection 7 8.0 [3.4;19.0]
Recent or current syphilis infection b , e 3
HIRI MSM score
  • 11 to 20 (vs. 10 or less)

5 2.7 [0.8;9.1]
  • 21 or more (vs. 10 or less)

24 8.4 [2.7;26.6]
Model with multiple risk factors
Age <30 years old 22 9.1 [3.2;26.2]
Number of anal sex partners (past 6 months)
  • 6 to 10 (vs. 5 or less)

10 5.3 [2.1;13.5]
  • 11 or more (vs. 5 or less)

15 8.4 [3.4;20.9]
Use of crystal methamphetamine during sex c 11 4.2 [1.5;11.6]
a

The concept of “cases observed for a given level of a variable” does not apply for a continuous variable.

b

Too few HIV cases were observed in at least one of the levels of the variable for reliable estimation.

c

Consumption in the 2 h before or during sex with at least one of the last five partners participants reported having sex with in the past 6 months.

d

Crystal methamphetamine, GHB (gammahydroxybutyrate), ecstasy/MDMA (3,4‐methylenedioxy‐methamphetamine), or ketamine consumption in the 2 h before or during sex with at least one of the last five partners participants reported having sex with in the past 6 months.

e

Reactive anti‐treponemal antibody test and rapid plasma reagin titer of 1/16+at baseline visit or new/reinfection at prospective visits.