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. 2022 Sep 30;49(12):1221–1227. doi: 10.1111/1346-8138.16596

TABLE 4.

Exacerbating factors associated with worsening rosacea, overall and by sex

Exacerbating factor, n (%) Phase 3 full analysis set (N = 130) Men (n = 23) Women (n = 107)
Temperature changes 70 (53.8) 11 (47.8) 59 (55.1)
Sun exposure 51 (39.2) 10 (43.5) 41 (38.3)
Hot weather 46 (35.4) 6 (26.1) 40 (37.4)
Seasonal variation 39 (30.0) 5 (21.7) 34 (31.8)
Heavy exercise 36 (27.7) 4 (17.4) 32 (29.9)
Emotional stress 32 (24.6) 5 (21.7) 27 (25.2)
Pollen 31 (23.8) 1 (4.3) 30 (28.0)
Alcohol 30 (23.1) 8 (34.8) 22 (20.6)
Menstrual cycle 25 (19.2) 0 25 (23.4)
Cold weather 24 (18.5) 3 (13.0) 21 (19.6)
Hot (temperature) foods 22 (16.9) 6 (26.1) 16 (15.0)
Use of cosmetics 16 (12.3) 0 16 (15.0)
Spicy foods 14 (10.8) 5 (21.7) 9 (8.4)
Others 15 (11.5) 2(8.7) 13(12.1)
None 10 (7.7) 3 (13.0) 7 (6.5)
None of the top five factors a 34 (26.2) 8 (34.8) 26 (24.3)

Note: More than one exacerbating factor could be selected per patient.

a

Temperature changes, sun exposure, hot weather, seasonal variation, heavy exercise.