Table 4.
ORs (95% CI) of IGT for 1 mIU/L increase of TSH or 1 unit of TSHI, TT4RI or PTFQI.
| No IGT | IGT | P value | |
|---|---|---|---|
| TSH (increase of 1 mIU/L) | |||
| Model 1 | 1.00 | 1.52 (1.18-1.96) | 0.001 |
| Model 2 | 1.00 | 1.41 (1.08-1.84) | 0.010 |
| TSH Index (increase of 1 unit) | |||
| Model 1 | 1.00 | 2.44 (1.45-4.09) | 0.001 |
| Model 2 | 1.00 | 2.15 (1.26-3.68) | 0.005 |
| TT4RI (increase of 1 unit) | |||
| Model 1 | 1.00 | 1.03 (1.01-1.04) | <0.0001 |
| Model 2 | 1.00 | 1.02 (1.01-1.04) | 0.004 |
| PTFQI (increase of 1 unit) | |||
| Model 1 | 1.00 | 7.49 (1.95-28.78) | 0.003 |
| Model 2 | 1.00 | 4.92 (1.25-19.39) | 0.023 |
Model 1: P value adjusted for centers, age and prepubertal stage.
Model 2: P value adjusted for centers, age, prepubertal stage, family history of type 2 diabetes,
HOMA-IR, TG/HDL ratio, systolic BP, obesity, IFG and high HbA1c.
TSH, thyroid stimulating hormone; TT4RI, Thyrotroph T4 Resistance Index; TFQI, Thyroid Feedback Quantile-based Index; PTFQI Parametric Thyroid Feedback Quantile-based Index; IGT, impaired glucose tolerance.