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. 2022 Oct 28;47(12):2110–2116. doi: 10.1111/ced.15327

Table 1.

Hormonal effects on the hair follicle. 8

Hormone Mechanism of action Impact on hair
Androgens Action via intracellular androgen receptor in the dermal papilla Face, axilla, pubic, chest hair: transformation of vellus to terminal hairs
Testosterone and dihydrotestosterone 5‐α reductase inhibitor converts testosterone to the more potent dihydrotestosterone Scalp hair: inhibitory
Oestrogen Binding to high‐affinity oestrogen receptors Impact remains under investigation, but thought to prolong anagen phase and reduce telogen phase
Progesterone Central action: inhibits LH secretion, which reduces androgen synthesis Further research is required to understand the impact of progesterone on the hair cycle. Possible action via androgens
Hair follicle: inhibits 5‐α reductase (reduces conversion of testosterone to dihydrotestosterone)

LH, luteinizing hormone.