Table 2.
Correlation analyses of clonal haematopoiesis of indeterminate potential with cardiovascular biomarkers
| Univariable | Multivariable1 | Multivariable2 | ||||
|---|---|---|---|---|---|---|
| Sβ (SE) | p‐value | Sβ (SE) | p‐value | Sβ (SE) | p‐value | |
| NT‐proBNP | +0.411 (0.098) | 0.000 | +0.222 (0.096) | 0.021 | +0.207 (0.086) | 0.019 |
| MR‐proANP | +0.443 (0.102) | 0.000 | +0.200 (0.096) | 0.038 | +0.195 (0.092) | 0.034 |
| Troponin T | +0.200 (0.099) | 0.043 | +0.015 (0.092) | 0.867 | ||
| CRP | −0.027 (0.100) | 0.785 | ||||
| MR‐proADM | +0.140 (0.103) | 0.177 | ||||
| CT‐proET‐1 | + 0.016 (0.104) | 0.881 | ||||
| Procalcitonin | −0.073 (0.104) | 0.484 | ||||
| PAI‐1 | −0.155 (0.099) | 0.117 | ||||
| Galectin‐3 | +0.127 (0.099) | 0.2 | ||||
| Cystatin C | +0.170 (0.102) | 0.096 | ||||
| UAE | −0.024 (0.098) | 0.804 | ||||
CRP, C‐reactive protein; CT‐proET‐1, C‐terminal pro‐endothelin‐1; MR‐proADM, mid‐regional pro‐adrenomedullin; MR‐proANP, mid‐regional pro‐A‐type natriuretic peptide; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; PAI, plasminogen activator inhibitor; Sβ, standardized regression coefficient; SE, standard error; UAE, urine albumin excretion.
Multivariable model 1 was adjusted for age and sex.
Multivariable model 2 was further adjusted for smoking, diabetes, hypertension, body mass index, cholesterol, history of myocardial infarction, atrial fibrillation and cerebrovascular accident.