TABLE 1.
Participant characteristics
| Total | Painful DPN | Non‐painful DPN | p value, painful vs. non‐painful | |
|---|---|---|---|---|
| N | 180 | 133 | 47 | |
| Demographic parameters | ||||
| Female (N, %) | 50 (27.7) | 41 (30.8) | 9 (19.5) | 0.1149 |
| Age in years (mean, SD) | 64.5 (10.1) | 63.3 (10.85) | 67.9 (6.93) | 0.0074* |
| Clinical parameters | ||||
| TCNS (mean, SD) | 10.73 (4.36) | 11.223 (4.4) | 9.31 (3.93) | 0.0093* |
| Diabetes duration in years (median, range) | 15 (0–46) | 15 (0.3–46) | 18 (0–44) | 0.4245 |
| Average foot pain rating (on a 0–10 numerical pain rating scale) 24 h prior to testing (mean, SD) | 3.25 (2.88) | 4.47 (2.5) | 0.48 (1.28) | <0.0001* |
| DFNS quantitative sensory testing on the foot | ||||
| Cold detection threshold (mean, SD) | −14.05 (9.5) | −14.72 (9.91) | −12.58 (8.42) | 0.1895 |
| Warm detection threshold (mean, SD) | 13.16 (3.87) | 13.26 (3.93) | 12.99 (3.74) | 0.6861 |
| Vibration detection threshold (mean, SD) | 5.05 (2.18) | 4.97 (2.12) | 5.16 (2.45) | 0.6128 |
Abbreviations: DFNS, German Research Network on Neuropathic Pain; DPN, diabetic polyneuropathy; TCNS, Toronto Clinical Neuropathy Score.
*
p value < 0.05.