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. 2023 Mar 21;19(6):1861–1874. doi: 10.7150/ijbs.82567

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EphA2 is highly expressed in BLBC and promotes breast cancer cell stemness. (A) According to database analysis (bc-GenExMiner v4.9), EphA2 mRNA levels were found to be highly expressed in basal-like breast cancers (BLBC); (B) According to TCGA database analysis, EphA2 mRNA levels were found to be highly expressed in BLBC patients; (C-I) After knockdown of EphA2 in HCC1937 and HCC1806 (C), flow detection of ALDH⁺ (D-E) and CD44⁺/CD24^-(F-G) cell ratios and mamosphere formation ratio was performed (H-I), Scale bar=250 μm; (J-K) Dilution tumorigenesis assay in nude mice (J), tumorigenesis rate statistics table (K).