TABLE 3.
Time 0 and time 24 BUN and creatinine across all doses
| Mean Creatinine Concentration (mg/dl) | Mean BUN Concentration (mg/dl) | |||
|---|---|---|---|---|
| Time 0 | Time 24 | Time 0 | Time 24 | |
| 2.5 mg/kg | 1.6 ± 0.2 | 1.3 ± 0.2 a | 27.8 ± 3.4 | 22.8 ± 3.3 a |
| 5 mg/kg | 1.7 ± 0.4 | 1.3 ± 0.3 a | 24.3 ± 1.3 | 17.0 ± 1.4 a |
| 10 mg/kg | 1.7 ± 0.2 | 1.5 ± 0.1 a | 25.5 ± 2.4 | 21.3 ± 3.4 a |
| 20 mg/kg | 1.6 ± 0.3 | 1.3 ± 0.2 a | 25.5 ± 3.7 | 19.0 ± 5.0 a |
| 40 mg/kg | 1.3 ± 0.2 | 1.3 ± 0.3 | 24.0 ± 1.4 | 20.5 ± 4.0 a |
| 80 mg/kg | 1.6 ± 0.3 | 1.4 ± 0.3 a | 28.0 ± 2.2 | 20.3 ± 3.0 a |
Note: A table presenting mean serum creatinine and BUN concentrations at time 0 and time 24 at each dose. The International Renal Interest Society considers 1.5 mg/dl to be the upper limit for normal creatinine concentration in cats. The normal reference value for BUN at the laboratory used in this study was 18–35 mg/dl. Values represent the mean creatinine and BUN values for all cats with standard deviation at time 0 and time 24. Statistical significance is denoted with an asterisk at time 24 when compared to time 0.
a
p value < .05 for significance.