Table 3.
Multivariable logistic regression for association between 24-month depression and regret, by prostate cancer risk group.
| Dependent Variable: High Depression at 24 Months | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Low Risk | Intermediate Risk | High Risk | |||||||
| OR | 95% CI | p-Value | OR | 95% CI | p-Value | OR | 95% CI | p-Value | |
| Regret score | 1.06 | 1.01, 1.11 | 0.0111 | 1.04 | 1.01, 1.08 | 0.0188 | 1.04 | 1.01, 1.07 | 0.0209 |
| Age | 0.98 | 0.89, 1.06 | 0.5402 | 1.03 | 0.96, 1.10 | 0.4154 | 0.96 | 0.89, 1.04 | 0.3199 |
| Number of people in household | 1.44 | 0.86, 2.42 | 0.1647 | 1.02 | 0.64, 1.65 | 0.9116 | 1.17 | 0.75, 1.83 | 0.4780 |
| Smoking | |||||||||
| Never | 0.22 | 0.10, 0.59 | 0.0031 | 0.51 | 0.22, 1.17 | 0.1136 | 1.06 | 0.48, 2.23 | 0.8900 |
| Current/ever (ref) | - | - | - | - | - | - | - | - | - |
| Insurance | |||||||||
| Medicare/Medicaid | 0.37 | 0.12, 1.17 | 0.0903 | 0.93 | 0.36, 2.37 | 0.8723 | 1.74 | 0.69, 4.39 | 0.2385 |
| Other (ref) | - | - | - | - | - | - | - | - | - |
| Treatment | |||||||||
| Surgery | 0.71 | 0.25, 2.05 | 0.5303 | 0.67 | 0.24, 1.87 | 0.4492 | 1.03 | 0.30, 3.61 | 0.9613 |
| Radiation | 0.39 | 0.07, 2.26 | 0.2956 | 0.44 | 0.12, 1.55 | 0.1998 | 2.47 | 0.53, 11.58 | 0.2497 |
| Active surveillance (ref) | - | - | - | - | - | - | - | - | - |
| Race | |||||||||
| White | 1.82 | 0.10, 35.70 | 0.6922 | 1.61 | 0.21, 12.24 | 0.6480 | 1.52 | 0.07, 32.60 | 0.7882 |
| African American | 2.37 | 0.07, 78.90 | 0.6304 | 3.34 | 0.29, 38.30 | 0.3322 | 3.26 | 0.12, 91.60 | 0.4875 |
| Other (reference) | - | - | - | - | - | - | - | - | - |
| Education | |||||||||
| College and more | 0.88 | 0.29, 2.59 | 0.8105 | 1.74 | 0.69, 4.36 | 0.2408 | 1.83 | 0.72, 4.65 | 0.2023 |
| Some college (ref) | - | - | - | - | - | - | - | - | - |
| Marital status | |||||||||
| Married | 0.45 | 0.09, 2.23 | 0.3305 | 0.67 | 0.21, 2.11 | 0.4957 | 0.97 | 0.24, 3.94 | 0.9678 |
| Other (ref) | - | - | - | - | - | - | - | - | - |
| Employment status | |||||||||
| Employed | 1.67 | 0.49, 5.69 | 0.4154 | 0.75 | 0.31, 1.85 | 0.5363 | 1.19 | 0.49, 2.92 | 0.6943 |
| Other (ref) | - | - | - | - | - | - | - | - | - |
| Income | |||||||||
| ≤USD 40,000 | 1.97 | 0.37, 10.55 | 0.4287 | 3.80 | 0.85, 17.72 | 0.4249 | 0.86 | 0.19, 3.76 | 0.8419 |
| USD 40–75,000 | 4.39 | 1.29, 14.98 | 0.0179 | 0.65 | 0.22, 1.88 | 0.0803 | 2.74 | 0.96, 7.75 | 0.0579 |
| >USD 75,000 (ref) | - | - | - | - | - | - | - | - | - |
| Study Site | |||||||||
| UPenn | 1.78 | 0.59, 5.34 | 0.2975 | 0.55 | 0.22, 1.36 | 0.1930 | 1.06 | 0.48, 2.34 | 0.5935 |
| FCCC/VA (ref) | - | - | - | - | - | - | - | - | - |
Abbreviations: UPenn, University of Pennsylvania; CMCVAMC, Corporal Michael J. Crescenz Veterans Administration Medical Center; FCCC, Fox Chase Cancer Center. OR: odds ratio. CI: confidence interval.