Figure 2.

Sub-groups analysis for BC recurrence rate by studies with >3-y RFS endpoints exploring heterogeneity according to categorical confounders (e.g., study, BCG, and NMIBC characteristics) (a). Forrest plot depicting BC recurrence rate by studies with >3-y RFS endpoints grouped by BCG strains and sorted by increasing effect size (b). Forrest-plot for cumulative meta-analysis by studies with >3-y RFS endpoints grouped according to BCG strain and sorted by year of publication (c). BC: Bladder Cancer; BCG: Bacillus Calmette–Guérin; Bladder Cancer; CHT: Chemotherapy; EAU: European Association of Urology.