Figure 5.

The RapidMiner decision tree model used to predict the development of metastasis. (A) The performance of the models obtained to predict the development of metastasis and the set of rules are shown in Figure S2A,B: disease-free survival is expressed in months; the Breslow Index in mm; L-BCL2⁺ represents the quantification of the intratumoral BCL2-positive lymphocytes expressed as No (absence of BCL2⁺ intratumoral lymphocytes), Low (presence of a small number of BCL2⁺ intratumoral lymphocytes), and High (presence of a large number of BCL2⁺ positive intratumoral lymphocytes); serum IL-4 is expressed in pg·mL⁻¹. (B) The RapidMiner decision tree model trained with the original 196 patients but without the attribute disease-free survival (see rules in Figure S3A). The attributes used to predict metastasis are Breslow index, stage according AJCC, and IL-6-serum levels in pg·mL⁻¹.