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. 2023 Mar 30;15(7):2079. doi: 10.3390/cancers15072079
Algorithm 1 Create tumor budding density map.
Ensure: The network was applied to the entire slide
  • 1:

    for every pixel in the WSI do         ▹ identified by its x and y coordinate

  • 2:

       Draw a circle with an area of 0.785 mm2.

  • 3:

       Count the number of tumor buds within each circle.

  • 4:

       Note the number of tumor buds within the circle on each (center) pixel of this circle.

  • 5:

    end for

  • 6:

    Normalize the density map based on the total number of tumor buds per slide.