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FUSCC treatment flowchart for patients with metastatic NF-PanNETs. A few patients received more than three lines of therapy, and some up to seven. CAPTEM: capecitabine and temozolomide; SSAs: somatostatin analogs; PRRT: peptide receptor radionuclide therapy. Locoregional treatment includes microwave ablation of the liver, transarterial chemoembolization, and transarterial embolization. Other chemotherapy includes capecitabine, carboplatin, fluorouracil, irinotecan, and oxaliplatin.
