Table 2.

Structural analysis of the PfBDP1-BRD (PDB ID: 7M97) compared to human bromodomains in families I–VIII.

Human bromodomain protein	PDB ID	Sequence identity %	RMSD value (calculated using PDBeFold)	Number of hydrophobic residues in binding pocket	Number of acidic residues in binding pocket	Number of basic residues in binding pocket
Family V TIF1α	3O33	39.58	0.88 Å	18	04	0
Family I CECR2	3NXB	36.76	0.92 Å	06	02	04
Family II BRD4	2OUO	36.59	1.21 Å	20	02	02
Family III CREBBP	3DWY	48.44	1.33 Å	10	02	01
Family VIII PB1(3)	3K2J	41.07	1.48 Å	14	04	03
Family IV ATAD2B	3LXJ	33.75	1.78 Å	15	03	03
Family VII TAF1	3UV5	38.10	2.00 Å	14	04	01
Family VI TRIM28	2RO1	22.95	2.07 Å	08	05	03