Table 2.
Oligo (IDH-mut&1p/19q-codeleted) |
Astro (IDH-mut) |
GBM (IDH-wt) |
p-Value | ||
---|---|---|---|---|---|
MRI-derived parameters | |||||
CBV (%) | Mean (std) | 1.43 (0.44) | 0.96 (0.36) | 1.20 (0.39) | 0.01 a |
Median (std) | 1.17 (0.36) | 0.70 (0.18) | 0.92 (0.37) | <0.001 b | |
Hot spot (std) | 3.31 (1.14) | 2.79 (1.71) | 3.34 (0.85) | 0.13 | |
µCBV (%) | Mean (std) | 1.45 (0.29) | 0.86 (0.26) | 1.36 (0.71) | <0.001 b |
Median (std) | 1.31 (0.25) | 0.74 (0.21) | 1.29 (0.73) | <0.001 b | |
Hot spot (std) | 2.37 (0.60) | 1.62 (0.77) | 2.22 (0.83) | 0.02 a | |
Vessel size () |
Mean (std) | 12.48 (2.61) | 15.55 (5.10) | 10.33 (3.62) | 0.01 a |
Median (std) | 10.18 (2.02) | 10.91 (2.47) | 7.02 (2.32) | 0.002 a | |
Hot spot (std) | 44.91 (15.55) | 78.85 (46.48) | 53.81 (34.96) | 0.06 a | |
Histopathology-derived parameters | |||||
Vessel density | Mean (std) | 3.69 (1.64) | 3.45 (2.09) | 6.47 (2.74) | 0.03 a |
Vessel radius () |
Mean (std) | 8.61 (1.92) | 8.72 (1.82) | 7.68 (1.70) | 0.55 b |
Vessel roundness | Mean (std) | 1.23 (0.03) | 1.20 (0.06) | 1.34 (0.03) | <0.001 a |