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Opposite effects upon ovary steroidogenesis of myo-Ins and D-Chiro-Ins. Insulin stimulation promotes the release of phosphoglycans, containing either myo-Ins (IPG-A) or D-Chiro-Ins (IPG-P). Moreover, insulin activates the epimerase-dependent transformation of myo-Ins into D-Chiro-Ins. Test, testosterone; DHEA, dehydroepiandrosterone; Cyp-19A, aromatase.
