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Mechanism of action of IL-17 inhibitors. Secukinumab and ixekizumab bind to IL-17A and inhibit its interaction with the IL-17 receptor. Bimekizumab binds to Il-17A and IL-17F and inhibits the activation of the IL-17RA/RC complex. Brodalumab binds to IL-17RA and blocks the actions of IL-17A,E,F.
