Figure 7.

Proposed approach to clinical assessment of symptomatic exacerbations of PTLD. *Lung function tests are generally not required at every clinical assessment or during an acute exacerbation but should be used as a diagnostic investigation and repeated to compare with baseline values when clinical deterioration is observed. ^†Based on a comparison of assessment findings with baseline assessment at end of TB treatment, and on results of current investigations. ^‡Can be initiated at any time during treatment or follow-up. mMRC = Modified Medical Research Council; 6MWT = 6-min walk test; ABG = arterial blood gas; BMI = body mass index; CXR = chest X-ray; ZN = Ziehl-Neelsen; NAAT = nucleic acid amplification test; FBC = full blood count; CRP = C-reactive protein; IgG = immunoglobulin G; PCR = polymerase chain reaction; PTLD = post-TB lung disease.