Table 8.

End-of-treatment testing for neurocognitive and functional impairment in children and adolescents with tuberculous meningitis (adapted from ¹⁹⁸)^*

Outcome	Measure
Neurodevelopmental	Minimal:  Ages and Stages Questionnaire250 (age range: 0–5 years) Optimal:  Bailey Scale of Infant Development251 (age range: 1–42 months)  Mullen Scale Early learning252 (age range: 0–68 months)
Neurocognitive	Wechsler Intelligence Scales for Children253 (age range: 6–16 years) Kauffman Assessment Battery for children. 2nd ed.254 (age range: 3–8 years)
Functional	Minimal:  Modified Rankin Scale255 (age range: 1 years–adult)  WHO Disability Assessment Schedule 2.0256 (age range: 12 years–adult) Optimal:  Vineland Adaptive Behaviour Scale257 (age range: birth to adult)
Neurobehavioural	Minimal:  Strengths and Difficulties Questionnaire258 (age range: 4–17 years) Child, parent, teachers’ forms

^* Assessments should be commenced 6–9 months after diagnosis and repeated long-term throughout schooling (2 and 5 years minimum). Note: The developmental assessment tools cited have not been formally adapted for use in low- and middle-income countries, nor have locally determined norms been developed. Therefore, interpretation of results requires careful consideration of the local context. An additional number of in-country locally developed screening tools are also available.