Table 2.

Selected obesity-related SNPs.

Gene Name	dbSNP rs#	Effect Allele	Context	References
ADCY3	rs11676272	G	missense_variant	[26,27,28,29,30,31]
AKAP6|NPAS3	rs17522122	G	3_prime_UTR_variant	[32,33,34,35,36]
ADPGK |ADPGK-AS	rs7164727	T	downstream_gene_variant	[32,34,35,37]
BDNF|BDNF-AS	rs6265	A	missense_variant	[29,33,35,38,39,40,41]
DNASE1	rs1053874	A	missense_variant	[37,42]
FAIM2|BCDIN3D	rs7138803	A	intergenic_variant	[27,29,32,33,34,35,36,37,38,43,44,45,46]
FLT3	rs1933437	C	missense_variant	[35]
FTO	rs1421085	C	intron_variant	[38]
FTO	rs7190492	A	intron_variant	[40]
GNPDA2	rs10938397	G	intergenic_variant	[27,29,32,33,34,35,36,37,38,43,44,45,47,48,49,50,51,52]
GPRC5B|GPR139|PDILT	rs12444979	T	intergenic_variant	[44]
HIVEP1	rs2228213	A	missense_variant	[33,34,35,38]
ITH4	rs4687657	T	missense_variant	[37]
KCTD15	rs11084753	A	intergenic_variant	[51]
LMOD1	rs2820312	A	missense_variant	[34,37,42,51]
LOC400652|LOC342784	rs17782313	C	intergenic_variant	[32,51,53,54]
MAF	rs1424233	T	regulatory_region_variant	[54]
MC4R	rs17700633	A	n/s	[53]
MST1R	rs2230590	C	missense_variant	[36,37,42]
MTCH2	rs3817334	T	intron_variant	[32,34,35,36,37,38,44,45]
NEGR1|LOC105378797	rs2815752	C	intron_variant	[44,51]
NPC1|SLC35F4	rs1805081	C	missense_variant	[54]
NT5C2	rs11191580	C	intron_variant	[36]
PCSK1	rs6235	C	missense_variant	[33]
POC5|FLJ35779	rs2112347	G	intergenic_variant	[29,32,33,34,35,36,37,38,43,44,45,48,50]
SEC16B	rs543874	G	upstream_gene_variant	[26,27,29,32,33,34,35,36,37,38,44,45,47,49,50,55,56,57]
SH2B1	rs7359397	T	intron_variant	[44]
STK33	rs10769908	C	intron_variant	[51]
TFAP2B	rs2206277	A	intron_variant	[29,33,36,38,43,58]
TMEM18	rs6548238	T	TF_binding_site_variant	[51]
TRAF3	rs10133111	A	3_prime_UTR_variant	[36,37]
UHRF1BP1	rs11755393	G	missense_variant	[37,42]
ZZZ3	rs17381664	C	intron_variant	[32,35,36,43]

Abbreviature: SNP, single nucleotide polymorphism.